Svensk Kirurgi nr 2-16

106 SVENSK KIRURGI • VOLYM 74 • NR 2 • 2016 Avhandlingsreferat kortare tid på uppvakningsavdelning (fyra respektive sex timmar; p=0,045) och kortare vårdtid (sex respektive nio dagar; p<0,05) jämfört med Hartmann’s operation. Slutsats Avhandlingens konklusion är att vid perforerad divertikulit medför Hartmann’s operation en betydande risk för re-operation, en dödlighet på sex procent och 40 procent kvarva- rande stomier. Laparoskopisk lavage som behandling vid perforerad diver- tikulit med purulent peritonit (Hin- chey III) reducerar risken för att re- opereras med 60 procent och minskar vårdbehovet.  Referenser 1. Hughes LE. Postmortem survey of diverti- cular disease of the colon. I. Diverticulosis and diverticulitis. Gut 1969; 10(5): 336-44. 2. Paspatis GA, Papanikolaou N, Zois E, Michalodimitrakis E. Prevalence of polyps and diverticulosis of the large bowel in the Cretan population. An autopsy study. International journal of colorectal disease 2001; 16(4): 257-61. 3. Jacobs DO. Clinical practice. Diverticuli- tis. The New England journal of medicine 2007; 357(20): 2057-66. 4. Strate LL. Lifestyle factors and the course of diverticular disease. Digestive diseases 2012; 30(1): 35-45. 5. Strate LL, Modi R, Cohen E, Spiegel BM. Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights. The American journal of gastro- enterology 2012; 107(10): 1486-93. 6. Chabok A, Pahlman L, Hjern F, Haapa- niemi S, Smedh K, Group AS. Randomi- zed clinical trial of antibiotics in acute uncomplicated diverticulitis. The British journal of surgery 2012; 99(4): 532-9. 7. Hinchey EJ, Schaal PG, Richards GK. Treatment of perforated diverticular disease of the colon. Advances in surgery 1978; 12: 85-109. 8. Thornell A, Angenete E, Haglind E. Perforated diverticulitis operated at Sahl- grenska University Hospital 2003-2008. Danish medical bulletin 2011; 58(1): A4173. 9. Myers E, Hurley M, O'Sullivan GC, Kavanagh D, Wilson I, Winter DC. Lapa- roscopic peritoneal lavage for generalized peritonitis due to perforated diverticulitis. The British journal of surgery 2008; 95(1): 97-101. 10. Thornell A, Angenete E, Gonzales E, et al. Treatment of acute diverticulitis laparosco- pic lavage vs. resection (DILALA): study protocol for a randomised controlled trial. Trials 2011; 12: 186. 11. Öresland T. Scandinavian Diverticuli- tis Trial. October 21, 2014. Available at https://clinicaltrialsgov/ct2/show/ NCT01047462?term=scandiv&rank=1 Accessed May 12, 2015. 12. Winter DC. LapLAND laparoscopic lavage for acute non-faeculant diverti- culitis. November 30, 2009. Available at https://clinicaltrialsgov/ct2/show/ NCT01019239?term=lapland&rank=1 Accessed May 12, 2015. 13. Swank HA, Vermeulen J, Lange JF, et al. The ladies trial: laparoscopic peritoneal lavage or resection for purulent peritonitis and Hartmann's procedure or resection with primary anastomosis for purulent or faecal peritonitis in perforated diverticuli- tis (NTR2037). BMC surgery 2010; 10: 29. 14. Thornell A, Angenete E, Bisgaard T, et al. Laparoscopic Lavage for Perforated Diverticulitis With Purulent Peritonitis: A Randomized, Controlled Trial. Annals of internal medicine 2016. 15. Schultz JK, Yaqub S, Wallon C, et al. Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: The SCANDIV Randomized Clinical Trial. Jama 2015; 314(13): 1364-75. 16. Vennix S, Musters GD, Mulder IM, et al. Laparoscopic peritoneal lavage or sig- moidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial. Lancet 2015. 17. Angenete E, Thornell A, Burcharth J, et al. Laparoscopic Lavage Is Feasible and Safe for the Treatment of Perforated Diverticulitis With Purulent Peritonitis: The First Results From the Randomized Controlled Trial DILALA. Annals of surgery 2014. Modern medical research is increasing in complexity, necessi - tating extensive collaboration and knowledge transfer between clinical and basic scientists. The Bengt Ihre Research School is an extension of the successful forum GIMIICum research school, now funded by the Bengt Ihre foundation and the Swedish Society of Gastroenterology. The aim of the school is to educate a new generation of investigators in gastroenterology who will apply team efforts in interdisciplinary research. Participating in the Bengt Ihre Research School The research school is a comprehensive course program that stretches over three years and seven separate 2-3 day cour - ses. Students enrolling in the program are expected to follow the complete course cycle. The course program is consistently translational and welcomes both clinical and basic PhD students. Bengt Ihre Research School is to be regarded as a complement to general scientific methodology courses taken at the home uni - versity. The course including meals and accommodation is free of charge, home institutions cover travel costs. Preliminary course program for the Research School • Introduction to translational research in gastroenterology, October 5-7, 2016 • Gastrointestinal physiology, January 11-13, 2017 • Gastrointestinal pathology and microbial pathogenesis, May 15-19, 2017 • Innate immunity of the gastrointestinal tract, October 4-6, 2017 • Adaptive immunity of the gastrointestinal tract, January, 2018 APPLICATION Who can apply? You should be registered as a PhD student (preferentially not beyond half time), or planned for registration within the next six months. How do I apply? The application should include: 1. Brief CV (maximum 2 pages) 2. Copy of certificate of registration for PhD studies, if applicable 3. Project plan (maximum 2 pages) 4. Letter of support from your main supervisor 5. Letter of support from your employer Deadline for application is June 3, 2016. Applications should be submitted in pdf format by e-mail to eva.m.danielsson@liu.se Assessment of your application All applications will be assessed and ranked by the Bengt Ihre Research School faculty. Criteria for assessment include: project within scope of research school, balance between clinicians and basic scientists and balance between universities. Decisions on admissions will be communicated by June 21, 2016. For more information please visit the homepage or contact eva.m.danielsson@liu.se BENGT IHRE RESEARCH SCHOOL